PG 55031.00 PU PP PG 54998.00 RD PP PG 55040 GN PP

PP POOF! PP POOF! PP POOF!

PP METAL BLUE SOLID RED PP GOLDEN PP

Fearon's cash fees included amounts earned for his service as Lead Director (January 1, 2023 - November 30, 2023) and Non-Executive Chairman (as of December 1, 2023) We used the following quarterly per share fair market values, calculated in accordance with Financial Accounting Standards Board Accounting Standards Codification Topic 718 (“FASB ASC Topic 718”), in calculating the number of shares: March 31, 2023 — $40.850 (857 shares); June 30, 2023 — $40.575 (863 shares); September 29, 2023 — $35.555 (984 shares); and December 29, 2023 — $41.990 (834 shares). A Named Executive Officer’s vested Supplemental Plan accounts will commence to be paid to them within 30 days of the date of their termination of employment with us in the form of payment they selected (lump-sum payment or payment in installments over a period not exceeding 10 years) on an election form received by us.

PROXY STATEMENT 2025 | Annual Meeting of Shareholders 30 Code of Ethics, Code of Conduct and Corporate Governance Guidelines In accordance with applicable NYSE listing standards and SEC regulations, the Board has adopted a Code of Ethics, Code of Conduct and Corporate Governance Guidelines. Long-Term Incentive Plan Vehicles and Weightings Cash Settled Performance Units 30% Stock Appreciation Rights 35% Restricted Stock Units 35% On February 22, 2024, we granted awards under the 2020 Plan to all of our Named Executive Officers, with the exception of Ms. A Named Executive Officer’s vested Supplemental Plan accounts will commence to be paid to them within 30 days of the date of their termination of employment with us in the form of payment they selected (lump-sum payment or payment in installments over a period not exceeding 10 years) on an election form received by us.

PG 311016.00 GN PP PG 311022.00 BU PP PINK 1767 PP

LIME GREEN 173218 PP PEARL WHITE PP LIGHT MAUVE PP

To demonstrate, Figure 11 shows how the mean strength of people with multiple sclerosis (PwMS) during a 30-second, sustained contraction is normalized to their maximal hand grip strength and compared to healthy controls.

PP GREY 498048 PP DEEP COBALT PP AQUA OCEAN

PG 261307.00 BU PP SL PG 261377.00 GN PP SL PP FR 8-6 LMS-1000