Food, Drug, Medical Drug Master Files FDA Drug Master Files and Medical Application Files. 

COMPREHENSIVE REGULATORY TESTING AND DOCUMENTATION Raw materials tested to: • ISO 10993-1 and USP , (biological evaluation) • European Pharmacopeia 3.1.3/3.1.5 (polyolefin —materials used for the manufacture of containers) • USP (polyethylene—plastic materials of construction) • ICH Q3D (elemental impurities) We provide Drug Master File (Type III) documentation and other supporting regulatory declarations that are relevant for the application. Mevopur color and performance concentrates as well as ready-to-use formulations add value to a wide range of applications: MEDICAL DEVICES • Drug delivery • Catheters • Renal care/dialysis • Surgical instruments • Dental instruments • Medical device packaging • Electronic instruments and accessories for monitoring PHARMACEUTICAL PACKAGING • Vials, ampoules • Bottles for pills, liquid medicines • Blister packaging IN VITRO DIAGNOSTICS (IVD) • Blood analysis • IVD devices • IVD disposables (e.g., pipette tips) • Point-of-Care To meet various manufacturing processes, colorants and functional additives are provided as concentrates for dilution into the polymer or as ready-to-use formulations.

All auto-injector designs and renderings in this presentation were produced by Avient Design for conceptual purposes Avient Corporation 3 Focus on Patient Journey Self Management & Self Administration Technology Driven Monitoring & Diagnostics Increased Drug Volumes Large Molecule Biologics Faster Injections Trends Patient and drug development needs are evolving at a rapid pace. Requirements: Sealing the syringe and displacing the medicant Temperature Control The expansion of new drugs for different disease states allows more patients to experience the convenience of auto-injectors. Thermal conductivity in a heat exchanger body help to warm and reduce the drug viscosity of biologics

INDUSTRY BULLETIN DISPERSIONS IN HEALTHCARE TECHNOLOGY DESCRIPTION TYPICAL APPLICATIONS Silicone Colorant Dispersions Biocompatible, conformable silicone rubber colorants that deliver lightfastness and aesthetic appeal • 3D medical silicone printing • Anatomical models and surgical guides • External prosthetics and orthotics • Medical ventilation/respiratory masks • Dental and medical tools and equipment Silicone Additive Dispersions Silicone additive solutions formulated to provide chemical resistance, durability, and enhanced physical properties Rubber Colorant Dispersions Durable rubber colorants formulated for optimal dispersion and lot-to-lot consistency to promote ease of handling • Medical devices and tools • Vibration and shock control for medical equipment • Drug delivery devices Urethane Colorant Dispersions Versatile urethane colorants that streamline production and enhance quality • Foam enclosures/support for medical tools and equipment • Medical and surgical devices • Physical therapy tools Epoxy Colorant Dispersions Long-lasting, hygienic epoxy colorants that provide high-cost efficiency, stability, and customization opportunities • Healthcare facility floor coatings Vinyl Colorant Dispersions Vinyl colorants developed for applications where dispersion, uniformity, compatibility, and cleanliness are essential • Medical equipment Aqueous Additive Formulations Functional additives stabilized, suspended, and dispersed in water that shorten development cycles, streamline operations, and can be customized to meet specific requirements • Medical gloves • Wound care Electrically Conductive Additives for Silicone Innovative silicone additives to provide high conductivity and lower filler loadings • Neurostimulation electrode pads • Medical tools and equipment Laser Marking Additives for Silicone Dispersions containing laser absorbers and color formers that eliminate the need for secondary etching while promoting chemical resistance, mechanical property retention, and production efficiency • 3D medical silicone printing • Anatomical models and surgical guides • External prosthetics and orthotics • Medical ventilation/respiratory masks • Medical devices Surface Modification Additives for Silicone Non-oil based silicone additives that reduce tackiness and enhance smoothness of the cured compound • Dental tools and equipment • Medical devices, tools, and equipment Self-Bonding Silicone Silicone compounds able to bond to various substrates without prime coating • Medical tools and equipment This listing represents standard Avient dispersion technologies and addresses common healthcare applications, but we can work with you to explore additional options.

FX • Driven by strong drug delivery sales, new business wins in building & construction and consumer • Higher sales and favorable mix more than offset by variable compensation reset resulting in lower adjusted EBITDA Copyright © . 2025 11 Specialty Engineered Materials - Q4 2024 performance 260 280 49 56 • Growth headlined by healthcare, including engineered materials in remote monitoring devices, as well as composites for building & construction, wind energy, and defense applications • Higher sales and favorable mix contributed to adjusted EBITDA growth which more than offset unfavorable impact of variable compensation FY 2024 Copyright © . 2025 13 Color, Additives & Inks – full year 2024 performance 2,007 2,047 358 384 • Driven by new applications for drug delivery and building & construction as well as demand recovery in packaging and consumer • Adjusted EBITDA margin expansion driven by higher sales and net price benefit Adj. 17.8% Adj. 18.7% Copyright © . 2025 14 Specialty Engineered Materials – full year 2024 performance 1,138 1,197 224 249 • Growth headlined by strong demand for applications in defense end market and composites used in building & construction and engineered materials used in healthcare • Adjusted EBITDA margin expansion driven by higher sales and favorable mix Adj. 19.7% Adj. 20.8% Copyright © . 2025 15 Avient full year 2024 performance vs. full year 2023 3,143 3,240 502 526 Adj.

Our internal Good Manufacturing Practices (GMP) guidelines govern the manufacture of intermediate products for our customer’s use in making food, drug and medical (FDM) final product applications. FDA Drug Master Files and Medical Application Files. 

Our internal Good Manufacturing Practices (GMP) guidelines govern the manufacture of intermediate products for our customer’s use in making food, drug and medical (FDM) final product applications. FDA Drug Master Files and Medical Application Files. 

Our internal Good Manufacturing Practices (GMP) guidelines govern the manufacture of intermediate products for our customer’s use in making food, drug and medical (FDM) final product applications. FDA Drug Master Files and Medical Application Files. 

Our internal Good Manufacturing Practices (GMP) guidelines govern the manufacture of intermediate products for our customer’s use in making food, drug and medical (FDM) final product applications. FDA Drug Master Files and Medical Application Files. 

The range is targeted for use in the production of pharma containers for parenteral, ocular, and nasal drugs. The colorant solutions are available in PP and PE (HDPE and LDPE) and produced with ingredients tested to European Pharmacopeia 3.1.3 and 3.1.5 as well as to USP chapters , including class VI (a requirement for ophthalmic and nasal drugs) and USP and (light transmission). Registered Drug Master File (DMF)