The nucleating agents also foster constant process settings throughout part manufacturing with a higher crystallization temperature for improved crystallization speed. REGULATORY SUPPORT • Drug delivery devices • Pharmaceutical packaging • Medical equipment KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing the risk of change • Allows crystallization in semi-crystalline polymers to begin faster and complete earlier REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

Consequently, you should not consider any such list to be a complete set of all potential risks or uncertainties. Name Age Position Robert M. The GeonTM brand name carries strong recognition globally.

We set an interim 2030 goal to attain 60% of our electricity from renewable sources. State of Ohio filings and contributions are publicly available at www.ohiosos.gov Those who file reports can remain anonymous.

Letter of Authority (LoA) for our Drug Master File (DMF) and Device Master File (MAF). Disclosure of ingredients for purpose of regulatory filings (under specific confidentiality agreements).

Letter of Authority (LoA) for our Drug Master File (DMF) and Device Master File (MAF). Disclosure of ingredients for purpose of regulatory filings (under specific confidentiality agreements).

Letter of Authority (LoA) for our Drug Master File (DMF) and Device Master File (MAF). Disclosure of ingredients for purpose of regulatory filings (under specific confidentiality agreements).

China TEL: +86 21 32799000 Zhu Hai Ming Management Representative Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid. ACCREDITED UNIT: DNV Business Assurance B.V., Zwolseweg 1, 2994 LB, Barendrecht, Netherlands - TEL: +31(0)102922689. www.dnv.com/assurance Certificate No: 2997-2006-AQ-RGC-RvA Initial certification date: 08 June, 2006 Valid: 11 April, 2022 – 11 April, 2025 This is to certify that the management system of Polyone - Suzhou, China EM Sector, 77 Shenggang Street, Suzhou Industrial Park, Suzhou, Jiangsu, China, 215024 and the sites as mentioned in the appendix accompanying this certificate has been found to conform to the Quality Management System standard: GB/T 19001-2016/ISO 9001:2015 This certificate is valid for the following scope: Design and Manufacture of Plastic Compounding Material Certificate No: 2997-2006-AQ-RGC-RvA Place and date: Shanghai, 27 April, 2022 Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid. ACCREDITED UNIT: DNV Business Assurance B.V., Zwolseweg 1, 2994 LB, Barendrecht, Netherlands - TEL: +31(0)102922689. www.dnv.com/assurance Page 2 of 2 Appendix to Certificate Polyone - Suzhou, China Locations included in the certification are as follows: Site Name Site Address Site Scope PolyOne Management (Shanghai) Co., Ltd.

China TEL: +86 21 32799000 Zhu Hai Ming Management Representative Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid. Park, Pudong, Shanghai China, 201203 and the sites as mentioned in the appendix accompanying this certificate has been found to conform to the Quality Management System standard: GB/T 19001-2016/ISO 9001:2015 This certificate is valid for the following scope: Design and Manufacture of Masterbatch Certificate No: 7071-1998-AQ-RGC-RvA Place and date: Shanghai, 19 March, 2021 Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid. TEL:+31(0)102922689. www.dnvgl.com/assurance Page 2 of 2 Appendix to Certificate PolyOne-Shanghai, China Locations included in the certification are as follows: Site Name Site Address Site Scope PolyOne Polymer (Tianjin) Company Limited No.28#C, Jin Bin Hi-Tech Industrial Park, 156 Nan Hai Road, Tianjin Economic-Technological, Tianjin, China, 300457 Manufacture of Masterbatch PolyOne-Shanghai, China No. 88, Guo Shou Jing Road, Z.

MSC Certificate Place and date: For the issuing office: Shanghai, 20 March 2024 DNV - Business Assurance Building 9, No. 1591 Hongqiao Road, Changning DistrictShanghai China 200336 Zhu Hai Ming Management Representative Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid. Park, China (Shanghai) Pilot Free Trade Zone, Shanghai, China 201203 and the sites as mentioned in the appendix accompanying this certificate has been found to conform to the Quality Management System standard: GB/T 19001-2016 / ISO 9001:2015 This certificate is valid for the following scope: Design and Manufacture of Colour and Additive Concentrates http://www.dnv.com/assurance Certificate no.: 7071-1998-AQ-RGC-RvA Place and date: Shanghai, 20 March 2024 Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid. ACCREDITED UNIT: DNV Business Assurance B.V., Zwolseweg 1, 2994 LB, Barendrecht, Netherlands - TEL: +31(0)102922689. www.dnv.com/assurance Page 2 of 2 Appendix to Certificate PolyOne-Shanghai, China Locations included in the certification are as follows: Site Name Site Address Site Scope PolyOne Polymer (Tianjin) Company Limited No. 28#C, Jin Bin Hi-Tech Industrial Park, No. 156, Nan Hai Road, Tianjin Economic- Technological Development Area, Tianjin, China 300457 Manufacture of Colour and Additive Concentrates PolyOne-Shanghai, China No. 88, Guo Shou Jing Road, Z.

We support your Device Master File submission for healthcare materials by developing and maintaining U.S. FDA Drug Master Files and Medical Application Files.