DOCUMENT NUMBER_ SSS-004 CATEGORY DETAIL EC Number 231-545-4 CAS Number 7631-86-9 Chemical Name Silicon Dioxide (SiO2) Structural Formula CHEMICAL IDENTITY Si O O DOCUMENT NUMBER_ SSS-004 HEALTH EFFECTS HUMAN HEALTH SAFETY ASSESSMENT Consumer No human health hazard has been identified relating to this substance.

F H H O m C H H O *C H H n C* H H O *m C H H C H C H C H H C H H C H *z C C C N HH H * x y C H 3 O C H 3 O* O C *n 285-056 Peel adhesion 3.23 2.55 3.06 3.063.063.062.89 2.55 2.89 2.89 2.72 2.72 3.06 2.38 0.00 0.50 1.00 1.50 2.00 2.50 3.00 3.50 Lexan 141 Cycolac MG38 Cycoloy C2950 Xenoy 5220 Xenoy 1339 Injection speed: 25 mm/sec A vg . p ee l, N /m m Melt temp: 190°C Melt temp: 200°C Melt temp: 220°C Figure 5: GLS 285-056 adhesion values overmolded onto PC, ABS, PC/ABS and PC/PBT over a wide range of melt emperatures of the TPE. t 285-056 peel adhesion 2.893.06 2.89 2.38 2.55 2.55 2.89 2.55 2.89 3.063.06 2.89 2 3 25 50 75 Injection velocity, mm/sec A vg . p ee l, N /m m Lexan 141 Cycolac MG38 Cycoloy C2950 Xenoy 5220 Figure 6: GLS 285-056 adhesion values overmolded onto PC, ABS, PC/ABS and PC/PBT over a wide range of injection peeds. s 285-056 tensile properties: initial & aged after 1 week at 70°C. 2.35 1.60 2.77 2.30 1.66 2.77 0 0.5 1 1.5 2 2.5 3 Tensile Strength 100% Modulus 300% Modulus P as ca ls Initial Final Figure 7: Physical property retention of GLS 285-056 after 1week at 70°C. OM6240 tensile properties: initial and final after 1 week at 70°C 2.8 1.8 2.6 2.8 1.8 2.6 0 0.5 1 1.5 2 2.5 3 Tensile Strength 100% Modulus 300% Modulus P as ca ls Initial Final Figure 8: Physical property retention of Versaflex OM 6240 after 1week at 70°C. OM6258 tensile properties after 1 week at 70°C 2.9 2.8 2.1 3 3.2 2.1 0 0.5 1 1.5 2 2.5 3 3.5 Tensile Strength 100% Modulus 300% Modulus P as ca ls Initial Final Figure 9: Physical Property retention of OM 6258 after 1 week at 70°C.

KEY CHARACTERISTICS • Available for polyethylene, polypropylene, ABS, polycarbonate and styrenics • Bio-content of resin carrier varies from 70% to 100% depending on polymer—calculated to ASTM D6866 standard • Manufactured at four ISO 13485 certified sites, providing global consistency and security of supply • Documented change control beyond CAS number, reducing risk of change • Drop-in solutions that can be processed like fossil-based grades on common injection molding and extrusion machines • Can be provided as ready-to-use pre-colored or additive formulation REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 - USP and (incl. class VI) - European Pharmacopeia, monograph 3.1.3/ 3.1.5 (polyolefin packaging materials) - USP (polyethylene) - Elemental impurities as per ICH Q3D • Registered Drug Master File (Type III) and/or Device Master File • Food contact according to US FDA and APPLICATION BULLETIN Sustainability Spotlight Bio-polymers Healthcare use limitations apply—see below.

REGULATORY SUPPORT • Drug delivery devices • Pharmaceutical packaging • Medical equipment KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing the risk of change • Allows crystallization in semi-crystalline polymers to begin faster and complete earlier REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing risk of change • Non-phthalate and formulated without animal-derived substances • Different tones of amber available on request —more or less red or yellow and/or lighter or darker • Also available in liquid form REGULATORY SUPPORT • Pre-tested raw materials: - ISO 10993-1 and USP parts (Class VI) - European Pharmacopeia, monograph 3.1.15, USP and elemental analysis as per ICH Q3D - USP criteria appearance of solution, color • Registered Drug Master File (Type III) by the FDA • Food contact compliance established with FDA/EU* • YBB00102002-2015 (oral liquid pharmaceutical PET bottles) compliance support APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number, reducing risk of change • Available as additive concentrates, ready-to-use additive formulations or ready-to-use additive/ colorant formulations for different polymers REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* APPLICATION BULLETIN * FDA/EU compliance information available upon request; exceptions may occur Healthcare use limitations apply—see below.

% Pigment Specific Gravity Color Index Lightfastness WHITE 10EPX03 Titanium Dioxide, Rutile 57 1.95 PW-6 I/O YELLOW 12EPX01 Diarylide AAOT GS 25 1.22 PY-14 I 12EPX03 Diarylide HR RS 20 1.2 PY-83 I/O (Mass) 13EPX02 Isoindolinone RS 30 1.3 PY-110 I/O 13EPX03 Benzimidazolone GS 40 1.27 PY-151 I/O (Mass) 81EPX01 Iron Oxide 40 1.62 PY-42 I/O ORANGE 15EPX03 Benzimidazolone 30 1.26 PO-36 I/O RED 23EPX04 Quinacridone BS 25 1.21 PV-19 I/O 23EPX06 Specialty Naphthol BS 30 1.21 PR-170 I/O (Mass) C 25EPX01 Red 2B, Ca Salt Bs 24 1.27 PR-48:2 I/O (Mass) 28EPX01 Red 2B, Ba Salt YS 23 1.29 PR-48:1 I/O (Mass) 82EPX01 Iron Oxide, Light BS 40 1.67 PR-101 I/O 82EPX02 Iron Oxide, Dark BVS 40 1.68 PR-101 I/O 82EPX04 Iron Oxide, Light VYS 40 1.67 PR-101 I/O BLUE 40EXP03 Phthalocyanine GS 25 1.25 PB-15:3 I/O 40EXP05 Phthalocyanine RS 25 1.25 PB-15:3 I/O 42EXP02 Ultramarine 50 1.54 PB-29 I/O 49EXP01 Cobalt 50 1.83 PB-28 I/O GREEN 50EPX02 Phthalocyanine BS 18 1.34 PG-7 I/O 50EPX03 Phthalocyanine YS 25 1.42 PG-7 I/O 59EPX01 Chromium Oxide 40 1.64 PG-17 I/O VIOLET/MAGENTA 24EPX03 Quinacridone Violet 15 1.2 PV-19 I/O 24EPX04 Ultramarine Violet 50 1.66 PV-15 I/O 24EPX05 Quinacridone Magenta 20 1.21 PR-122 I/O 24EPX06 Benzimidazolone 20 1.2 PV-32 I/O 24EPX07 Carbazole Violet 15 1.2 PV-23 I/O BROWN/TAN 83EPX01 Iron Oxide, Light 39 1.64 PBr-6 I/O 83EPX02 Iron Oxide, Dark 40 1.66 PBr-6 I/O BLACK 90EPX01 Furnace - High Jet 14 1.23 PBk-7 I/O 90EPX04 Furnace - Medium 20 1.25 PBk-7 I/O 90EPX05 Iron Oxide 50 1.77 PBk-11 I/O EPX RS = Red Shade YS = Yellow Shade VYS = Very Yellow Shade BS = Blue Shade VBS = Very Blue Shade GS = Green Shade HR = Heat-Resistant LIGHTFASTNESS I = Indoor Only I/O = Indoor or Outdoor Mass = Outdoor Masstone Application Only C = Some Caution Advised www.avient.com Copyright © 2020, Avient Corporation.

DOCUMENT NUMBER_ SSS-003 CATEGORY DETAIL EC Number 215-175-0 CAS Number 1309-64-4 Name Subclass 1 Antimony Trioxide (ATO) Structural Formula CHEMICAL IDENTITY PROPERTY DETAIL Physical State Solid Form Powder Color White Odor Odorless Melting Point 656°C Boiling Point 1425°C Bulk Density 5.20 g/cm3 Water Solubility Slightly Soluble PHYSICAL/ CHEMICAL PROPERTIES DOCUMENT NUMBER_ SSS-003 HEALTH EFFECTS HUMAN HEALTH SAFETY ASSESSMENT Consumer It is very unlikely that consumers would be exposed to ATO in its concentrated form because it is only sold for industrial use to make polymers and other products and is not sold directly to consumers.

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