Because the trays were regularly handled by consumers and filled with food, it was very important that any changes made to the material would not jeopardize the packaging’s FDA compliance. Even more importantly, the additive technology met FDA-compliance, so the improved packaging was delivered without any service interruption to the end customer, saving the converter thousands of dollars in packaging redesign efforts, and solidifying the sheet producer’s relationship with their valuable customer.

APPLICATIONS • Medical devices • Drug delivery devices • Labware KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing risk of change REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* * FDA/EU compliance information available upon request Copyright © 2023, Avient Corporation. It is the responsibility of the medical device manufacturer and the person placing the medical device on the market to ensure compliance of the medical device with all applicable laws and regulations, including the suitability of all raw materials and components used for its manufacture.

Hygiene fiber manufacturer HYGIENE FIBER MANUFACTURER P P N O N W O V E N M U L T I L A Y E R S • Meet FDA requirements specified by the customer • Provide technical support including specific color, processing and molding recommendations • Deliver the brighter white colorants to make the final product look whiter and cleaner • Developed an FDA colorant to meet customer regulatory specifications • Provided technical expertise throughout the design and manufacturing process • Offered a brighter white color for the final product Remafin Fiber Colorants for PP KEY REQUIREMENTS WHY AVIENT? AVIENT SOLUTION COMPLIANCE + TECHNICAL SUPPORT LEARN MORE Copyright © 2024, Avient Corporation.

LEADING PRODUCER OF CLOSURES FOR SPIRITS L U X U R Y C L O S U R E S • Replace metal while providing metallic look and feel • Customization of density and color • Easy processing • FDA compliance • Replaced metal with a weighted polymer solution to maintain high-quality perception • Minimized the appearance of chips from everyday wear better than metal by matching closure interior and metalized coating colors • Enabled the customer to introduce their luxury closures to a new market segment Gravi-Tech™ Density Modified Formulation KEY REQUIREMENTS WHY AVIENT? https://www.avient.com/products/engineered-polymer-formulations/eco-conscious-formulations/gravi-tech-density-modified PRODUCTOR LÍDER DE TAPONES PARA BEBIDAS ALCOHÓLICAS T A P O N E S D E L U J O • Se sustituye el metal al mismo tiempo que se ofrece aspecto y sensación metálicos • Personalización de densidad y color • Procesamiento sencillo • Cumplimiento con las normas de la FDA • El metal se sustituye con un compuesto plástico de densidad modificada para mantener una percepción de alta calidad • Se redujo al mínimo la aparición de desportilladuras por el desgaste cotidiano, que supera al metal porque permite hacer coincidir el interior de la tapa con los colores de revestimiento metalizado • Permitió al cliente introducir sus tapones de lujo en un nuevo segmento del mercado Formulación de densidad modificada Gravi- Tech™ REQUERIMIENTOS CLAVE ¿POR QUÉ AVIENT?

This verification opinion declaration applies to the related information included within the scope of work described below. Cleveland, Ohio Doral, Florida September 25, 2024 This verification declaration including the opinion expressed herein, is provided to Avient and is solely for the benefit of Avient in accordance with the terms of our agreement. We consent to the release of this declaration by you to the public or other organizations but without accepting or assuming any responsibility or liability on our part to any other party who may have access to this declaration.

REGULATORY SUPPORT • Drug delivery devices • Pharmaceutical packaging • Medical equipment KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing the risk of change • Allows crystallization in semi-crystalline polymers to begin faster and complete earlier REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below. It is the responsibility of the medical device manufacturer and the person placing the medical device on the market to ensure compliance of the medical device with all applicable laws and regulations, including the suitability of all raw materials and components used for its manufacture.

With robust raw material testing and a comprehensive change control policy, these medical-grade concentrates and pre-colored formulations can help minimize risk and avoid non-compliance. KEY CHARACTERISTICS • Globally harmonized formulations are manufactured at four ISO 13485 certified medical sites, providing global consistency and increased security of supply • Documented change control available • A range of standard colors eliminates color matching to expedite development time • The portfolio includes compliant colors for use in: - Needle hub applications: ISO 6009 - Ophthalmic container closures (American Academy of Ophthalmology) REGULATORY SUPPORT • A library of pre-tested raw materials including: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* HEALTHCARE APPLICATIONS • Medical devices such as catheters, surgical and dental instruments, and drug delivery devices • Pharmaceutical packaging including vials and bottles • Diagnostics for blood analysis or In Vitro Diagnostics (IVD) PRODUCT BULLETIN & COLOR CARD * FDA/EU compliance information available upon request; exceptions may occur Color Pantone Reference PE Base PP Base Transparent PP Base PEBA Base PC Base Transparent PC Base* ABS Base* White — PE0M176031 PP0M176045 ** AH0M415001 NC0M176058 ** SB0M665206 Yellow 102C PE1M176076 PP1M176060 PP1M176062 AH1M415002 NC1M176058 NC1M176059 SB1M664958 Orange 158C PE2M176044 PP2M176046 ** ** NC2M176044 NC2M664912 SB2M664939 Red 199C PE3M176131 PP3M176111 PP3M176113 AH3M415002 NC3M176116 NC3M176122 SB3M665037 Pink 196C PE3M176130 PP3M176109 ** AH3M415001 NC3M176117 NC3M665052 SB3M665039 Violet 2593C PE4M176023 PP4M176036 PP4M176039 AH4M415001 NC4M176038 NC4M176044 SB4M664978 Light Blue 292C PE5M176155 PP5M176169 ** AH5M415003 NC5M176142 ** SB5M665402 Mid Blue 285C PE5M176154 PP5M176171 PP5M176175 AH5M415002 NC5M176143 NC5M176146 SB5M665404 Dark Blue 288C PE5M176153 PP5M176173 ** ** NC5M176144 ** SB5M665406 Light Green 346C PE6M176128 PP6M176111 ** ** NC6M176118 ** SB6M665070 Bluish Green 3145C PE6M176126 PP6M176115 ** ** NC6M176119 ** SB6M665068 Medium Green 348C PE6M176127 PP6M176113 PP6M176118 AH6M415001 NC6M176120 NC6M176121 SB6M665072 Dark Gray 425C PE7M176066 PP7M176091 PP7M176094 ** NC7M176124 ** SB7M665297 Mid Gray Cool Gray 5C PE7M176067 PP7M176089 ** AH7M415001 NC7M176125 NC7M665175 SB7M665295 Beige 7502C PE8M176048 PP8M176058 ** ** NC8M176058 ** SB8M664871 Brown 463C/731C PE8M176049 PP8M176060 ** ** NC8M176059 ** SB8M664869 Black Black C PL9M176008 PP9M176017 ** ** NC9M176008 NC9M176009 SB9M664896 Colors may vary from actual color shown. It is the responsibility of the medical device manufacturer and the person placing the medical device on the market to ensure compliance of the medical device with all applicable laws and regulations, including the suitability of all raw materials and components used for its manufacture.

Homepage // News Center // Avient Showcases New Sustainable Solutions and Recent Compliance Certifications at ITMA 2023 MILAN, Italy – June 7, 2023 – Avient Corporation is debuting a new, sustainable solution for textile dyes and highlighting recently achieved compliance certifications for color & additives for synthetic fibers at the start of ITMA 2023, the world’s largest annual international textile and garment technology exhibition June 8-14 in Milan, Italy. Avient’s Taoyuan production site in Taiwan recently achieved full compliance with the Global Recycled Standard (GRS) 4.0.

KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number, reducing risk of change • Available as additive concentrates, ready-to-use additive formulations or ready-to-use additive/ colorant formulations for different polymers REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* APPLICATION BULLETIN * FDA/EU compliance information available upon request; exceptions may occur Healthcare use limitations apply—see below. It is the responsibility of the medical device manufacturer and the person placing the medical device on the market to ensure compliance of the medical device with all applicable laws and regulations, including the suitability of all raw materials and components used for its manufacture.

This verification opinion declaration applies to the related information included within the scope of work described below. Miami, Florida Santa Ana, California July 26, 2022 This verification opinion declaration, including the opinion expressed herein, is provided to Avient and is solely for the benefit of Avient in accordance with the terms of our agreement. We consent to the release of this declaration by you to CDP in order to satisfy the terms of CDP disclosure requirements but without accepting or assuming any responsibility or liability on our part to CDP or to any other party who may have access to this declaration.