Mevopur™ Healthcare Colorants and Formulations Amber Colorants for Pharmaceutical Packaging Avient constantly monitors the evolution of regulations in the healthcare industry, and develops compliant products well before those regulations go into effect. Mevopur Healthcare Colorants and Formulations in amber tones provide the safety of pre-tested raw materials while protecting and prolonging the shelf life of pharmaceuticals and nutraceuticals in amber PET packaging products. KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing risk of change • Non-phthalate and formulated without animal-derived substances • Different tones of amber available on request —more or less red or yellow and/or lighter or darker • Also available in liquid form REGULATORY SUPPORT • Pre-tested raw materials: - ISO 10993-1 and USP parts (Class VI) - European Pharmacopeia, monograph 3.1.15, USP and elemental analysis as per ICH Q3D - USP criteria appearance of solution, color • Registered Drug Master File (Type III) by the FDA • Food contact compliance established with FDA/EU* • YBB00102002-2015 (oral liquid pharmaceutical PET bottles) compliance support APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

Mevopur™ Healthcare Colorants and Formulations Special Effect Colorants for Healthcare Devices and Pharmaceutical Packaging Self-administered medication, for example via pen devices and inhalers, has been the norm for many years. Ingredients used in the Mevopur™ portfolio have been tested to industry standards that support applications in both medical devices and pharmaceutical packaging.* KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified manufacturing sites, providing global consistency and increased security of supply • Documented change control beyond CAS number, reducing risk of change • Non-phthalate and formulated without animal-derived substances • Available as pre-colored formulation or concentrate and for use in different polymers REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU** APPLICATION BULLETIN * Design note: Effect colors require careful consideration of part design and polymer flow paths to minimize visible flow lines.

LIQUID COLOR AMBAR 489-10122-3 LIQUID COLOR AMBAR 489-10438-1 LIQUID COLOR HERSHEY BROWN 489-20141-1

LIQUID COLOR SILVER LIQUID COLOR GOLD LIQUID COLOR YELLOW

LIQUID COLOR WHITE LIQUID COLOR AMBER LIQUID COLOR BLUE

LIQUID COLOR PEARL PINK LIQUID COLOR AMARILLO LIQUID COLOR BLUE

LIQUID COLOR YELLOW 486-33492-3 LIQUID COLOR YELLOW 486-33593-1 LIQUID COLOR YELLOW 486-33615-1

LIQUID COLOR BLUE 485-90237-1 LIQUID COLOR CYPRESS GREEN LIQUID COLOR BLUE

WT PE COLOR CONCENTRATE WT PE COLOR CONCENTRATE WT PE COLOR CONCENTRATE

LIQUID COLOR BRIGHT RED 483-32322-3 LIQUID COLOR GREEN 348C 484-20424-1 LIQUID COLOR AQUA 16-5127 TPX